The following gene names and symbols are associated with antigen MCOPS3 across different species:

SRY (sex determining region Y)-box 2 (SOX2)

Other aliases include:

ANOP3, MCOPS3, MGC2413

On the protein level the following designations are being used for antigen MCOPS3:

sex-determining region Y-box 2 – transcription factor SOX2 – SRY-related HMG-box gene 2

MCOPS3 fulfills a number of functions:

chromatin binding – protein binding – sequence-specific DNA binding – transcription factor activity

MCOPS3 is relevant to the following processes:

adenohypophysis development – anatomical structure formation involved in morphogenesis – cell fate specification – cerebral cortex development – chromatin organization – detection of mechanical stimulus involved in equilibrioception – detection of mechanical stimulus involved in sensory perception of sound – diencephalon morphogenesis – embryonic organ development – forebrain neuron differentiation – inner ear morphogenesis – lens induction in camera-type eye – male genitalia development – negative regulation of Wnt receptor signaling pathway – negative regulation of neuron differentiation – negative regulation of osteoblast differentiation – negative regulation of transcription from RNA polymerase II promoter – neuron fate commitment – olfactory placode formation – pigment biosynthetic process – positive regulation of Notch signaling pathway – positive regulation of neuroblast proliferation – positive regulation of neuron differentiation – positive regulation of transcription from RNA polymerase II promoter – regulation of transcription, DNA-dependent – response to chemical stimulus – response to retinoic acid – retina morphogenesis in camera-type eye – stem cell maintenance – tongue development

Locations for MCOPS3:

cytoplasm – nucleus – transcription factor complex

资源: NCBI Entrez Gene, Gene Ontology