购物车
帮助
产品细节
anti-AICARFT/IMPCHASE (ATIC) antibody
概述
| 抗原: | AICARFT/IMPCHASE (ATIC) |
| 克隆: | 单克隆抗体 (F38 P7 H9) |
| 应用范围: | Western Blotting (WB) |
| 目标物种: | Human, Frog, Fruit Fly (Drosophila melanogaster), Rat (Rattus), Mouse (Murine) |
| 抗体来源: | Mouse |
| 规格: | |
| 价格: | 2.276,03 ¥ (加上运费和增值税, Invoice in EUR) |
| 货号: | ABIN307123 |
| 发货时间: | Ships within 5 to 10 Business Days |
详细信息 » anti-AICARFT/IMPCHASE (ATIC) antibody
| 抗原 | AICARFT/IMPCHASE (ATIC) |
| Swiss-Prot | P31939 |
| 目标物种 | Human, Frog, Fruit Fly (Drosophila melanogaster), Rat (Rattus), Mouse (Murine) |
| 抗体来源 | Mouse |
| 克隆 | 单克隆抗体 |
| 抗体同种型 | IgG1 »相配的二抗 |
| 描述 | The bifunctional purine biosynthesis protein PURH contains phosphoribosylaminoimidazole carboxamide formyltransferase, also designated AICAR transformylase, IMP cyclohydrolase or Inosinicase. AICAR plays an important role in purine biosynthesis, specifically in the production of nucleotides and IMP. Defects in ATIC, the gene encoding for this protein, can cause AICArebosuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic. Individuals with AICA-rebosuria accumulate AICA-ribotide, also designated ZMP, and its derivatives in erythrocytes and fibroblasts and also excrete very large amounts of AICA-riboside in the urine. Mental retardation, epilepsy, dysmorphic features and congenital blindness are all symptoms of this disease. Synonyms: AICAR, AICARFT, AICARFT/IMPCHASE, PURH, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. |
| 克隆 | F38 P7 H9 |
使用细节 » anti-AICARFT/IMPCHASE (ATIC) antibody
| 应用范围 | Western Blotting (WB) |
| 应用备注 | Antibody can be used for Western blotting (1-2 ug/ml) and immunohistochemistry on formalin-fixed, paraffin-embedded tissues (1-5 ug/ml). Positive Control: Colorectal cancer tissue.. |
| 贮藏 | Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles |
| 限制 | For Research Use only |
抗原
