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anti-quinone reductase 1 (NQO1) antibody

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图像 anti-quinone reductase 1 (NQO1) antibody
抗原: Quinone reductase 1 (NQO1)
克隆: 多克隆抗体
应用范围: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
目标物种: Human
抗体来源: Goat
5 references available 5 references available
规格: 100 ug
价格: 2.305,71 ¥   (加上运费和增值税, Invoice in EUR)
货号: ABIN184714
发货时间: Ships within 5 Business days
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详细信息  » anti-quinone reductase 1 (NQO1) antibody

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抗原 Quinone reductase 1 (NQO1)
基因ID 1728 , 18104 (mouse)
免疫原 C-SIPTDNQIKARK
目标物种 Human
克隆 多克隆抗体
状态 Affinitiy-purified
描述 All names and symbols: NQO1, NAD(P)H dehydrogenase, quinone 1, DTD, QR1, DHQU, DIA4, NMOR1, NMORI, diaphorase-4, diaphorase (NADH/NADPH), diaphorase (NADH/NADPH) (cytochrome b-5 reductase), NAD(P)H:menadione oxidoreductase 1, dioxin-inducible 1. Official Symbol: NQO1. RefSeq number(s): NP_000894.1, NP_001020604.1, NP_001020605.1. Gene ontology terms: NAD(P)H dehydrogenase (quinone) activity, cytochrome b5 reductase activity, nitric oxide biosynthesis, response to toxin, synaptic transmission, cholinergic, xenobiotic metabolism, electron transport, cytoplasm, oxidoreductase activity
抗体来源 Goat
特异性 This products is expected to recognize all three reported isoforms (NP_000894.1, NP_001020604.1 and NP_001020605.1). Human, Mouse, Rat 274 aa

使用细节  » anti-quinone reductase 1 (NQO1) antibody

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应用范围 ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
应用备注 Peptide ELISA: antibody detection limit dilution 1:64,000. Western Blot: Approx. 30kDa band observed in Human Kidney and Lung lysates (calculated MW of 30.9kDa according to NP_000894.1). Recommended concentration: 0.03-0.1µg/ml.
纯化 Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
贮藏 Aliquot and store at -20°C. Minimize freezing and thawing.
研究领域 Metabolism, Drugs
限制 For Research Use only

参考文献  » anti-quinone reductase 1 (NQO1) antibody

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参考文献 Asher, Lotem, Kama et al.: "NQO1 stabilizes p53 through a distinct pathway." In: Proceedings of the National Academy of Sciences of the United States of America , Vol. 99, Issue 5, pp. 3099-104, 2002 (PubMed)

van Horssen, Schreibelt, Boe et al.: "NAD(P)H:quinone oxidoreductase 1 expression in multiple sclerosis lesions." In: Free radical biology & medicine , Vol. 41, Issue 2, pp. 311-7, 2006 (PubMed)

Ritz, Wan, Diaz-Sanchez: "Sulforaphane-stimulated phase II enzyme induction inhibits cytokine production by airway epithelial cells stimulated with diesel extract." In: American journal of physiology. Lung cellular and molecular physiology , Vol. 292, Issue 1, pp. L33-9, 2007 (PubMed)

Tanaka, Aleksunes, Cui et al.: "ANIT-induced intrahepatic cholestasis alters hepatobiliary transporter expression via Nrf2-dependent and independent signaling." In: Toxicological sciences : an official journal of the Society of Toxicology , Vol. 108, Issue 2, pp. 247-57, 2009 (PubMed)

Schriner, Avanesian, Liu et al.: "Protection of human cultured cells against oxidative stress by Rhodiola rosea without activation of antioxidant defenses." In: Free radical biology & medicine , Vol. 47, Issue 5, pp. 577-84, 2009 (PubMed)