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抗原
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Adrenocorticotropic Hormone
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Swiss-Prot
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P01189
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免疫原
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Keyhole Limpet Haemocyanin conjugated human ACTH (1-17)
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目标物种
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Human, Rat (Rattus)
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克隆
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单克隆抗体
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状态
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Purified
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抗体同种型
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IgG1 »相配的二抗
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描述
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ACTH, released from the anterior pituitary gland in response to corticotropin-releasing hormone from the hypothalamus, acts on the adrenal cortex to stimulate the production of corticosteroids such as cortisol, involved in the response to stress. Studies have shown that the administration of 1-24 ACTH increases blood pressure, believed to be attributed to an increase in ACTH-stimulated cortisol secretion, in association with increased cardiac output.
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克隆
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57
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抗体来源
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Mouse
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特异性
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This antibody recognises 1-24 ACTH (Synacthen) which, as a synthetic analogue of naturally- occurring Adrenocorticotropic Hormone, can be used to measure adrenal reserve and for the diagnosis of adrenal insufficiency by acute adrenocortical stimulation. It does not recognise 17-39 ACTH (CLIP).
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